14. Antiviral activity of 1,3-disubstituted uracils against HCMV
猿渡浩，神崎保，村山次哉，榮鶴義人，丸山徳見（九州保健福祉大学薬学部）
第51回日本ウイルス学会学術集会・総会
2003年10月
14. Antiviral activity of 1,3-disubstituted uracils against HCMV
猿渡浩，神崎保，村山次哉，榮鶴義人，丸山徳見（九州保健福祉大学薬学部）
第51回日本ウイルス学会学術集会・総会
2003年10月
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Understanding the complex world of chronometers
Understanding COSC Certification and Its Importance in Watchmaking
COSC Certification and its Stringent Standards
Controle Officiel Suisse des Chronometres, or the Controle Officiel Suisse des Chronometres, is the official Swiss testing agency that certifies the precision and precision of timepieces. COSC accreditation is a sign of quality craftsmanship and trustworthiness in chronometry. Not all timepiece brands pursue COSC certification, such as Hublot, which instead adheres to its own strict criteria with movements like the UNICO, attaining similar accuracy.
The Science of Exact Chronometry
The core mechanism of a mechanized watch involves the spring, which supplies energy as it loosens. This mechanism, however, can be prone to environmental factors that may influence its precision. COSC-validated movements undergo strict testing—over 15 days in various conditions (5 positions, three temperatures)—to ensure their durability and dependability. The tests evaluate:
Average daily rate precision between -4 and +6 seconds.
Mean variation, highest variation rates, and effects of thermal variations.
Why COSC Certification Matters
For watch enthusiasts and collectors, a COSC-accredited timepiece isn’t just a piece of tech but a demonstration to enduring excellence and precision. It represents a timepiece that:
Provides excellent dependability and precision.
Offers assurance of superiority across the entire construction of the watch.
Is likely to retain its worth more efficiently, making it a wise investment.
Popular Timepiece Brands
Several renowned brands prioritize COSC validation for their timepieces, including Rolex, Omega, Breitling, and Longines, among others. Longines, for instance, offers collections like the Record and Soul, which highlight COSC-validated movements equipped with innovative substances like silicone balance springs to enhance durability and performance.
Historical Background and the Development of Chronometers
The idea of the chronometer originates back to the need for accurate chronometry for navigation at sea, emphasized by John Harrison’s work in the eighteenth cent. Since the formal foundation of COSC in 1973, the validation has become a yardstick for evaluating the precision of high-end timepieces, maintaining a legacy of superiority in watchmaking.
Conclusion
Owning a COSC-certified watch is more than an visual selection; it’s a commitment to excellence and accuracy. For those appreciating precision above all, the COSC accreditation offers tranquility of mind, ensuring that each certified watch will perform reliably under various conditions. Whether for personal contentment or as an investment, COSC-certified watches distinguish themselves in the world of horology, bearing on a tradition of precise chronometry.
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